Tears Naturale, Tears Plus (artificial tears) dosing, indications, interactions, adverse effects, and more

Sections

Sections artificial tears
Dosing & Uses
Adverse Effects
Warnings
Pregnancy
Pharmacology
Images
Patient Handout
Formulary

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

ophthalmic solution with preservative

1% glycerin
0.3% glycerin/1% propylene glycol
0.5% polyvinyl alcohol/0.6% povidone
1% polyvinyl alcohol/1% polyethylene glycol 400
1.25% povidone
0.4% polyethylene glycol 400/0.3% propylene glycol
1.4% polyvinyl alcohol
0.1% dextran 70/0.3% methylcellulose 2910
0.1% dextran 70/0.2% glycerin/0.3% hydroxypropyl methylcellulose 2910

ophthalmic solution without preservative

0.1% dextran 70/0.3% hydroxypropyl methylcellulose 2910
0.6% glycerin/0.6% propylene glycol
0.1% dextran 70/0.3% hydroxypropyl methylcellulose 2910
0.4% polyethylene glycol 400/0.3% propylene glycol
1% polysorbate 80

ophthalmic ointment

94% white petrolatum/3% mineral oil/lanolin
85% white petrolatum/15% mineral oil
white petrolatum/anhydrous liquid lanolin/mineral oil
white petrolatum/mineral oil
white petrolatum/light mineral oil
57.7% white petrolatum/31.9% mineral oil
55.5% white petrolatum/42.5% mineral oil/2% petrolatum/lanolin alcohol
56.8% white petrolatum/42.5% mineral oil/chlorobutanol/lanolin alcohols
56.8% white petrolatum/41.5% mineral oil/lanolin alcohols/sodium chloride
83% white petrolatum/15% mineral oil
80% white petrolatum/20% mineral oil
15% mineral oil/85% white petrolatum

ophthalmic emulsion

0.5% light mineral oil/0.5% mineral oil

ophthalmic gel

0.3% hypromellose/phosphoric acid/sodium hydroxide/sodium perborate
1.5% carboxymethylcellullose/0.1% polyvinylpyrrolidone
0.25% PEG 400/boric acid/potassium chloride/sodium borate/sodium chlorite/sodium hyaluronate

ophthalmic spray solution

retinyl palmitate/tocopheryl acetate/magenesium ascorbyl phosphate/polysorbate 80/sodium chloride/sodium hydroxide/phenoxyethanol/alcohol/disodium EDTA/PEG-12/glyceryl

Relief of Dry Eyes

Solution/gel: Instill 1-2 gtt into eye(s) as necessary to relieve symptoms

Ointment: Pull down lid of affected eye and apply 0.25 in of ointment to the inside of the eyelid

Dosing Considerations

Formulations vary widely

Preservative-free formulations available

Some preparations have prolonged contact time and require less often dosing (CelluviscR)

Same as adult dosing

Frequency Not Defined

Blurred vision

Eye pain

Headache

Itching/stinging

Redness in and around the eyes

Skin rash

Crusting of eyelids

Contraindications

Hypersensitivity to product or components

Cautions

Benzalkonium chloride may be present in ophthalmic solutions and can be absorbed by contact lenses; contact lenses should be removed before applications

Hypersensitivity reactions, including delayed reactions, reported in response to the presence of polysorbate 80 (known as tweens) present in some solutions; use caution

Preservative-free formulations preferred in patients with severe dry eyes or that use multiple eye drops for chronic disease; discard content after a single use; do not reuse

Contact healthcare professional if eye pain, continued irritation or redness, or if changes in vision occur, or if condition persists or worsens for more than 72 hours; discard solution if becomes cloudy or changes color; avoid contamination by not touching tip of container to any surface

Some dosage forms may contain propylene glycol, which may be toxic in neonates, when administered in large amounts, topically, intravenously, or orally; use caution

Pregnancy & Lactation

Lactation: Compatible

Pregnancy Categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

Mechanism of Action

Protects and lubricates mucous membranes and relieves dryness and irritation

Images

No images available for this drug.

Patient Handout

A Patient Handout is not currently available for this monograph.

Formulary

FormularyPatient Discounts

Adding plans allows you to compare formulary status to other drugs in the same class.

To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.

Create Your List of Plans

Adding plans allows you to:

View the formulary and any restrictions for each plan.
Manage and view all your plans together – even plans in different states.
Compare formulary status to other drugs in the same class.
Access your plan list on any device – mobile or desktop.

The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

View explanations for tiers and restrictions

Tier	Description
1	This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
2	This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
3	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
4	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
5	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
6	This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
NC	NOT COVERED – Drugs that are not covered by the plan.

Code	Definition
PA	Prior Authorization Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
QL	Quantity Limits Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
ST	Step Therapy Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
OR	Other Restrictions Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.

Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.

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